Not FDA-Approved — Research Use Only

GHK-Cu

Sold and regulated as a cosmetic ingredient (INCI: Copper Tripeptide-1); no FDA drug approval applies.

GHK-Cu is a naturally occurring copper-binding tripeptide whose plasma concentration declines with age. In dermal fibroblast and keratinocyte research, it stimulates collagen and glycosaminoglycan syn...

PubChem CID71587328
FormulaC14H23CuN6O4+
Mol. Weight402.92 g/mol

Sequence

Mechanism of Action

GHK-Cu is a naturally occurring copper-binding tripeptide whose plasma concentration declines with age. In dermal fibroblast and keratinocyte research, it stimulates collagen and glycosaminoglycan synthesis, promotes angiogenesis, and has chemotactic effects on immune cells, and it has been shown to influence broad gene-expression programs linked to tissue remodeling and wound repair.

Copper(II) chelationFibroblast/keratinocyte gene expression programs

Research Literature