Sermorelin
Sermorelin corresponds to the biologically active N-terminal 1-29 fragment of human growth hormone-releasing hormone (GHRH). It binds the pituitary GHRH receptor, activating Gs/adenylate cyclase/cAMP ...
PubChem CID16132413
FormulaC149H246N44O42S
Mol. Weight3357.9 g/mol
Sequence
Mechanism of Action
Sermorelin corresponds to the biologically active N-terminal 1-29 fragment of human growth hormone-releasing hormone (GHRH). It binds the pituitary GHRH receptor, activating Gs/adenylate cyclase/cAMP signaling that drives pulsatile growth hormone release, and has historically been used both as a diagnostic probe of pituitary GH reserve and as a chronic-dosing research tool for the GHRH axis.
GHRH receptor (GHRH-R)